For 60 years, people have relied on Purdue over-the-counter products for the treatment of occasional constipation (or irregularity). In 2002, Purdue acquired Colace® and Peri-Colace® to offer more options for treating occasional constipation. Additionally, in 2015, Purdue introduced Colace Clear Soft Gels, the first stool softener available that is dye-free and also gluten-free. (Other non-prescription medications for occasional constipation from Purdue include the Senokot® laxatives and Peri-Colace.)

Active Ingredient in Colace Is a Stool Softener, Not a Stimulant

The active ingredient in Colace—docusate sodium—is not a stimulant but a stool softening laxative that allows water and fats to enter the stool, which helps to hydrate and soften the stool, making natural defecation more comfortable.

Colace Clear Soft Gels Provide a Dye-Free, Gluten-Free Option

For those who want to avoid dye, or who prefer gluten‑free products, Colace Clear® Soft Gels provide gentle, dependable relief from occasional constipation. This Colace product is a stool softener, and does not contain a stimulant laxative.

Peri-Colace Contains a Stool Softener and a Stimulant Laxative

The active ingredients in Peri-Colace are docusate sodium, a stool softener, and standardized senna concentrate, a stimulant laxative. Recommend Peri-Colace to your patients who require more than just a stool softener. (Learn more about senna in laxatives.)


  • Do not use laxative products for longer than 1 week unless told to do so by a doctor.
  • Do not use if you are presently taking mineral oil unless told to do so by a doctor.
  • Ask a doctor before use if you have:
    • Stomach pain
    • Nausea
    • Vomiting
    • Noticed a sudden change in bowel habits that lasts over two weeks
  • Stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use of a laxative. These could be signs of a serious condition.
  • If pregnant or breastfeeding, ask a health professional before use.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Offers Savings and More

Visit for information about constipation, senna, healthy recipes, and more. Can Help You Understand and Manage Constipation

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The prescription and illicit opioid abuse crisis is a multifaceted public health challenge, and as a manufacturer of prescription opioids, we have a responsibility to join the fight. At Purdue we are committed to lead our industry in helping address our nation's prescription and illicit opioid abuse crisis.

There is more to come – as we continue to work with partners and experts to deliver solutions. Below you will find additional information about our efforts.

Read our open letter about the opioid crisis.