For 60 years, people have relied on Purdue over-the-counter products for the treatment of occasional constipation (or irregularity). In 2015, Purdue introduced Colace Clear® Soft Gels, the first stool softener available that is dye-free and also gluten-free. (Other non-prescription medications for occasional constipation from Purdue include the Senokot® laxatives and Colace 2-IN-1)

Active Ingredient in Colace Is a Stool Softener, Not a Stimulant

The active ingredient in Colace—docusate sodium—is not a stimulant but a stool softening laxative that allows water and fats to enter the stool, which helps to hydrate and soften the stool, making natural defecation more comfortable.

Peri-Colace Contains a Stool Softener and a Stimulant Laxative

The active ingredients in Peri‑Colace are docusate sodium, a stool softener, and standardized senna concentrate, a stimulant laxative. Recommend Peri‑Colace to your patients who require more than just a stool softener. (Learn more about senna in laxatives.)

Colace Clear Soft Gels Provide a Dye-Free, Gluten-Free Option

For your patients who want to avoid dye, or who prefer gluten‑free products, Colace Clear® Soft Gels provide an option for gentle, dependable relief from occasional constipation. This Colace product is also stimulant-free.

Warnings for your patients:

  • Do not use laxative products for longer than 1 week unless told to do so by a doctor.
  • Do not use if you are presently taking mineral oil unless told to do so by a doctor.
  • Ask a doctor before use if you have:
    • Stomach pain
    • Nausea
    • Vomiting
    • Noticed a sudden change in bowel habits that lasts over two weeks
  • Stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use of a laxative. These could be signs of a serious condition.
  • If pregnant or breastfeeding, ask a health professional before use.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Offers Patient Savings and More

Visit—and recommend it to your patients—for information about constipation, healthy recipes, and more. Can Help Your Patients Understand and Manage Constipation

Visit—and recommend it to your patients—for information about constipation, good nutrition with balanced meals, and more.

The prescription and illicit opioid abuse crisis is a multifaceted public health challenge, and as a manufacturer of prescription opioids, we have a responsibility to join the fight. At Purdue we are committed to lead our industry in helping address our nation's prescription and illicit opioid abuse crisis.

There is more to come – as we continue to work with partners and experts to deliver solutions. Below you will find additional information about our efforts.

Read our open letter about the opioid crisis.